Personnel Information

写真a

IKURA Teikichi


Job title

Associate Professor

Laboratory Phone number

+81-3-5803-4594

Graduating School 【 display / non-display

  • Kyoto University, Faculty of Science, 1988, Graduated

Graduate School 【 display / non-display

  • Kyoto University, Graduate School, Division of Natural Science, Department of Chemistry, Doctor's Course, 1993, Completed

Degree 【 display / non-display

  • Doctor of Science, Kyoto University

Campus Career 【 display / non-display

  • 2003.04
    -
    2012.03
    Tokyo Medical and Dental University, Biomedical Science PhD Program / Graduate School of Biomedical Science, Associate Professor
  • 2012.04
    -
    2016.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Advanced Therapeutic Sciences, Structural Biology, Associate Professor
  • 2012.04
    -
    Now
    Tokyo Medical and Dental University, Medical Research Institute, Advanced Molecular Medicine, Structural Biology, Associate Professor
  • 2016.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Life Science and Technology, Life Science and Technology, Structural Biology, Associate Professor

Qualification Acquired 【 display / non-display

  • X-ray Work Chief Person

 

Published Papers & Misc 【 display / non-display

  • Masuno Hiroyuki, Kazui Yuko, Tanatani Aya, Fujii Shinya, Kawachi Emiko, Ikura Teikichi, Ito Nobutoshi, Yamamoto Keiko, Kagechika Hiroyuki. Development of novel lithocholic acid derivatives as vitamin D receptor agonists BIOORGANIC & MEDICINAL CHEMISTRY. 2019.08; 27 (16): 3674-3681. ( PubMed, DOI )

  • Nakayama S, Shimonaka S, Elahi M, Nishioka K, Oji Y, Matsumoto SE, Li Y, Yoshino H, Mogushi K, Hatano T, Sato T, Ikura T, Ito N, Motoi Y, Hattori N. Tau aggregation and seeding analyses of two novel MAPT variants found in patients with motor neuron disease and progressive parkinsonism. Neurobiology of aging. 2019.03; ( PubMed, DOI )

  • Yurina Miyashita, Nobutaka Numoto, Sundaram Arulmozhiraja, Shogo Nakano, Naoya Matsuo, Kanade Shimizu, Osamu Shibahara, Michiko Fujihara, Hiroki Kakuta, Sohei Ito, Teikichi Ikura, Nobutoshi Ito, Hiroaki Tokiwa. Dual conformation of the ligand induces the partial agonistic activity of retinoid X receptor α (RXRα). FEBS Lett.. 2019.01; 593 (2): 242-250. ( PubMed, DOI )

  • Teikichi Ikura, Yasushige Yonezawa, Nobutoshi Ito. Mutational effects of Cys113 on structural dynamics of Pin1 Biophysics and Physicobiology. 2019;

  • Teikichi Ikura, Naoya Tochio, Ryosuke Kawasaki, Mizuki Matsuzaki, Akihiro Narita, Mahito Kikumoto, Naoko Utsunomiya-Tate, Shin-Ichi Tate, Nobutoshi Ito. The trans isomer of Tau peptide is prone to aggregate, and the WW domain of Pin1 drastically decreases its aggregation. FEBS Lett.. 2018.09; 592 (18): 3082-3091. ( PubMed, DOI )

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Books etc 【 display / non-display

  • Arai, M., Ito, K., Maki, K., Ikura, T., Inobe, T., Kihara, H., Amemiya, Y., Kuwajima, K. Structural analysis of protein folding intermediates by solution X-ray scattering. Old and New Views of Protein Folding, 31-40 ISBN : 0444502912. Excerpta Medica, 1999

  • Maki, K., Ikura, T., Mohs, A., Kuwajima, K. Equilibrium and kinetics of folding of staphylococcal nuclease and its proline mutants. Old and New Views of Protein Folding, 271-278. Excerpta Medica, 1999 (ISBN : 0444502912)

  • Ikura, T., Go, N. Computational analysis of site-directed mutants of mouse epidermal growth factor. Computer Aided Innovation of New Materials, II, 1315-1318.. North Holland, 1993 (ISBN : 044489778X)

Conference Activities & Talks 【 display / non-display

  • Teikichi Ikura, Nobutoshi Ito. Micronization of a protease derived from Pin1. The 57th annual meeting of the Biophysical Society of Japan 2019.09.25

  • Teikichi Ikura, Yasushige Yonezawa and Nobutoshi Ito. A single mutation C113A caused drastic change in the dynamic of Pin1. Joint Annual Meeting of 71st JSCB & 19th PSSJ 2019.06.25 Kobe City

  • Teikichi Ikura. Hierarchical aspects in protein function. 2019.02.14 Kyoto

  • Teikichi Ikura, Naoya Tochio, Ryosuke Kawasaki, Mizuki Matsuzaki, Akihiro Narita, Mahito Kikumoto, Naoko Utsunomiya-Tate, Shin-ichi Tate, Nobutoshi Ito. The trans isomer of Tau peptide is prone to aggregate, and WW domain of Pin1 drastically decreases its aggregation. The 41st Annual Meeting of the Molecular Biology Society of Japan 2018.11.29 Yokohama

  • Teikichi Ikura and Nobutoshi Ito. Mutational analysis on the catalytic site of a protease derived from Pin1. The 56th Annual Meeting of the Biophysical Society of Japan 2018.09.15

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Campus class subject 【 display / non-display

  • Lecture of Structural Biology,2012 - 2015

  • Special Lecture of Structural Biology,2003 - Now