Personnel Information

写真a

Kazuhiro AOKI


Job title

Professor

Birth date

1961

Laboratory Address

No. 217 2nd Fl. Build No.2, 1-5-45, Yushima, Bunkyo-ku, Tokyo

Laboratory Phone number

+81358034641

Laboratory Fax number

+81-3-5803-4641

Mail Address

kazu.hpha@tmd.ac.jp

Homepage URL

http://www.tmd.ac.jp/english/ohe/BOHS_551299de5b5da/index.html

Research Areas, Keywords

Development of bone anabolic agents, non-invasive method of bone augmentation, Development of surface coating materials for the prevention of plaque growth,Research related to the connection between oral bacteria and systemic diseases

Profile

http://www.tmd.ac.jp/english/artis-cms/cms-files/Press_9.pdf

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Dentistry, Faculty of Dentistry, 1988, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Dental Research, Dental Pharmacology, Doctor's Course, 1992, Completed

Degree 【 display / non-display

  • Ph.D, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 1995.04
    -
    2009.03
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Pharmacology, Assistant Professor
  • 2009.04
    -
    2017.01
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Bio-Matrix, Pharmacology, Associate Professor
  • 2017.02
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Science and Technology, Basic Oral Health Engineering, Professor

External Career 【 display / non-display

  • 1992.10
    -
    1995.03
    , Dentist
  • 1997.10
    -
    1999.09
    Yale University Faculty of Medicine, Department of Cell Biology, Postdoctoral fellow (Prof. Roland Baron's Lab)
  • 2010.08
    -
    2012.07
    Ministry of Education, , Program officer

Academic Society Affiliations 【 display / non-display

  • American Society of Bone and Mineral Research

  • International Association of Dental Research

  • Japanese Pharmacological Society

Research Areas 【 display / non-display

  • Functional basic dentistry

Qualification Acquired 【 display / non-display

  • Dentist

 

Published Papers & Misc 【 display / non-display

  • Touyama K, Khan M, Aoki K, Matsuda M, Hiura F, Takakura N, Matsubara T, Harada Y, Hirohashi Y, Tamura Y, Gao J, Mori K, Kokabu S, Yasuda H, Fujita Y, Watanabe K, Takahashi Y, Maki K, Jimi E. Bif-1/Endophilin B1/SH3GLB1 regulates bone homeostasis. Journal of cellular biochemistry. 2019.06; ( PubMed, DOI )

  • Sone E, Noshiro D, Ikebuchi Y, Nakagawa M, Khan M, Tamura Y, Ikeda M, Oki M, Murali R, Fujimori T, Yoda T, Honma M, Suzuki H, Ando T, Aoki K. The induction of RANKL molecule clustering could stimulate early osteoblast differentiation. Biochemical and biophysical research communications. 2019.02; 509 (2): 435-440. ( PubMed, DOI )

  • Ikebuchi Yuki, Aoki Shigeki, Honma Masashi, Hayashi Madoka, Sugamori Yasutaka, Khan Masud, Kariya Yoshiaki, Kato Genki, Tabata Yasuhiko, Penninger Josef M., Udagawa Nobuyuki, Aoki Kazuhiro, Suzuki Hiroshi. Coupling of bone resorption and formation by RANKL reverse signalling NATURE. 2018.09; 561 (7722): 195-200. ( PubMed, DOI )

  • Urata Mariko, Kokabu Shoichiro, Matsubara Takuma, Sugiyama Goro, Nakatomi Chihiro, Takeuchi Hiroshi, Hirata-Tsuchiya Shizu, Aoki Kazuhiro, Tamura Yukihiko, Moriyama Yasuko, Ayukawa Yasunori, Matsuda Miho, Zhang Min, Koyano Kiyoshi, Kitamura Chiaki, Jimi Eijiro. A peptide that blocks the interaction of NF-B p65 subunit with Smad4 enhances BMP2-induced osteogenesis JOURNAL OF CELLULAR PHYSIOLOGY. 2018.09; 233 (9): 7356-7366. ( PubMed, DOI )

  • Cui Xinnan, Murakami Tatsuya, Tamura Yukihiko, Aoki Kazuhiro, Hoshino Yu, Miura Yoshiko. Bacterial Inhibition and Osteoblast Adhesion on Ti Alloy Surfaces Modified by Poly(PEGMA-r-Phosmer) Coating ACS APPLIED MATERIALS & INTERFACES. 2018.07; 10 (28): 23674-23681. ( PubMed, DOI )

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Conference Activities & Talks 【 display / non-display

  • Ayaka Urakawa, Masud Khan, Yosuke Sasaki, Michiko Ozawa, Kazunari Akiyoshi, and Kazuhiro Aoki. An investigation of scaffold materials suitable for new bone anabolic agents. 1st Meeting of the International Oral Engineering Consortium 2018.09.24 Tokyo, Japan

  • N. Wakabayashi, H. Inagawa, N. Suzuki, K. Aoki, T. Yamazaki, C. Watanabe, N. Murakami.. Validity of Young's Modulus Estimated Based on Computed Tomography. 96th General Session & Exhibition of the IADR 2018.07.28 London, England

  • Kazuhiro AOKI. Roland gave me a seed of my research. The 59th Annual Meeting of Japanese Association for Oral Biology 2017.09.16 Matsumoto Dental University

  • Mikami R, Aoki A, Mizutani K, Tamura Y, Aoki K, Izumi Y. Low-level blue laser irradiation enhances osteoblast proliferation and differentiation. The 102nd Annual Meeting of the American Academy of Periodontology 2016.09.10 San Diego Convention Center(USA)

  • Md.Zahirul Haque Bhuyan, Chizuko Maeda, Yuki Yoshinari, Marin Kawasaki, Yasutaka Sugamori, Genki Kato, Mariko Takahashi, Yukihiko Tamura, Kazuhiro Aoki. The therapeutic effects of the RANKL-binding peptides on cartilage destruction.. 13th Bone Biology Forum 2016.08.20 Cross Wave Makuhari (Chiba)

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Awards & Honors 【 display / non-display

  • The 2nd prize of the student competition at the 1st Meeting of International Oral Health Engineering Consortium (Ayaka Urakawa) ,2018.09

  • New Investigator Award(Uehara T), 13th Congress of the Internatitonal Society of Bone Morphometry,2015.04

Others 【 display / non-display

  • The Wnt agonist R-spondin 3: an unexpected negative regulator of bone formation,2017.11

    Special lecture for PhD course student
    Dr. Kenichi Nagano Department of Oral Medicine, Infection and Innunity, Harvard School of Dental Medicine

 

Social Contribution 【 display / non-display

  • Science Diaglog (Dr. Masud Khan and Prof Kazuhiro Aoki),JSPS,Public school of Sagamihara juniro high school in Kanagawa prefecture,2018.01.20