Personnel Information

写真a

AZUMA Miyuki


Job title

Professor

Laboratory Address

1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8549, Japan

Laboratory Phone number

+81-3-5803-5935

Research Areas, Keywords

Immunology, Oral immunology, tumor immunology, immune regulation

Graduating School 【 display / non-display

  • Tokyo Medical and Dental University, Faculty of Dentistry, Dentistry, 1984.03, Graduated

Graduate School 【 display / non-display

  • Tokyo Medical and Dental University, Graduate School, Division of Dental Research, Oral Surgery, Doctor's Course, 1988.03, Completed

Degree 【 display / non-display

  • DDS, PhD, Tokyo Medical and Dental University

Campus Career 【 display / non-display

  • 1988.04
    -
    1990.02
    Tokyo Medical and Dental University, Faculty of Dentistry, Dental Resident
  • 1992.10
    -
    1993.03
    Tokyo Medical and Dental University, Faculty of Dentistry, Assistant Professor
  • 2000.04
    -
    Now
    Tokyo Medical and Dental University, Graduate School of Medical and Dental Sciences, Medical and Dental Sciences, Oral Health Sciences, Molecular Immunology, Professor

External Career 【 display / non-display

  • 1990.03
    -
    1992.10
    Department of Immunology, DNAX Research Institute for Molecular and Cellular Biology, CA, USA, Postdoctral fellow
  • 1990.03
    -
    1992.09
    Becton Dickinson Immunocytometry Systems , Visiting Scientist
  • 1993.04
    -
    1996.03
    Juntendo University School of Medicine, , School of Medicine, Department of Immunology, Assistant professor
  • 1996.04
    -
    2000.03
    National Children's Medical Research Center , Department of Immunology, Staff Scientist

Academic Society Affiliations 【 display / non-display

  • Japanese Society for Immunology,

  • Japanese Stomatological Society

  • Japanese Cancer Association

  • American Association of Immunologists

  • The Stomatological Society,Japan

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Research Areas 【 display / non-display

  • Immunology

  • Pathobiological dentistry/Dental radiology

Qualification Acquired 【 display / non-display

  • Dentist

 

Published Papers & Misc 【 display / non-display

  • Hidetake Tachinami, Naoto Nishii, Yulong Xia, Yoshihisa Kashima, Tatsukuni Ohno, Shigenori Nagai, Lixin Li, Walter Lau, Kei Tomihara, Makoto Noguchi, Miyuki Azuma. Differences of tumor-recruiting myeloid cells in murine squamous cell carcinoma influence the efficacy of immunotherapy combined with a TLR7 agonist and PD-L1 blockade. Oral Oncol.. 2019.04; 91 21-28. ( PubMed, DOI )

  • Emi Furusawa, Tatsukuni Ohno, Shigenori Nagai, Taisei Noda, Takuya Komiyama, Katsunori Kobayashi, Hidetoshi Hamamoto, Michiyo Miyashin, Hiroo Yokozeki, Miyuki Azuma. Silencing of PD-L2/B7-DC by Topical Application of Small Interfering RNA Inhibits Elicitation of Contact Hypersensitivity. J. Invest. Dermatol.. 2019.04; ( PubMed, DOI )

  • Alastair Copland, Adam Sparrow, Peter Hart, Gil Reynolds Diogo, Mathew Paul, Miyuki Azuma, Rajko Reljic. Bacillus Calmette-Guérin Induces PD-L1 Expression on Antigen-Presenting Cells via Autocrine and Paracrine Interleukin-STAT3 Circuits. Sci Rep. 2019.03; 9 (1): 3655. ( PubMed, DOI )

  • Mulati K, Hamanishi J, Matsumura N, Chamoto K, Mise N, Abiko K, Baba T, Yamaguchi K, Horikawa N, Murakami R, Taki M, Budiman K, Zeng X, Hosose Y, Azuma M, Konishi I, Mandai M. VISTA expressed in tumour cells regulates T cell function. Br. J. Cancer. 2019.01; 120 (1): 115-127. ( PubMed, DOI )

  • Azuma T, Sato Y, Ohno T,Azuma M, Kume H.. Serum soluble B7-H4 is a prognostic marker for patients with non –metastatic clear cell renal cell carcinoma. Plos One. 2018.07; 13 (7): e01997119. ( DOI )

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Books etc 【 display / non-display

  • Azuma M, Oki S. In: Kishimoto T., eds. Leukocyte Typing VI: White cell differentiation antigens. Garland Publishing Inc New York & London, 1997 CD28 workshop panel report

Conference Activities & Talks 【 display / non-display

  • Furusawa E, Ohno T, Miyashin M, Azuma M. Topical application of B7-DC/PD-L2 siRNA inhibits contact hypersensitivity. 15th International Symposium on Dendritic Cells 2018.06.10 Aachen,Germany

  • Nishii N, Tachinami H, Kondo Y, Xia Y, Kashima Y, Ohno T, Nagai S, Li L, Lau W, Harada H, Azuma M. Systemic administration of a TLR7 agonist attenuates regulatory T cells by dendritic cell modification and overcomes resistance to PD-L1 blockade therapy. 15th International Symposium on Dendritic Cells 2018.06.10 Aachen,Germany

  • Azuma M. Immune regulation in the oral cavity. Tokyo medical and Dental University-Taipei Medical University Joint Symposium 2016.11.12 Taiwan

  • Kang S, Ohno T, Azuma M. Prickle cells in the dorsal surface of tongue and gingiva spontaneously express an immunoregulatory molecule CD274 (B7-H1). The 56th Annual Meeting of Japanese Association for Oral Biology 2014.09.25 Fukuoka,Japan

  • 大野 建州、東 みゆき. 新規抑制性共刺激分子VISTAのT細胞依存的あるいは非依存的免疫応答における役割解析. 第56回歯科基礎医学会 2014.09.25 福岡

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Awards & Honors 【 display / non-display

  • Astra Award (Japanese Association of allergy),1998

  • Hajime Memorial Award (DNAX research institute),1992